Chlonidine 15 mcg Intrathecal as Prevention in Incidence of Post Spinal Anesthesia Shivering on Caesarea Surgery

Nurul Ulfah Hayatunnisa


Background: The aim of this study is to know whether klonidin 15 mcg intrathecal can prevent incidence of shivering in pregnant woman who undergoing caesarea surgery with spinal anesthesia.

Methods: In this double blind study, 178 parturients women with physical status ASA I-II undergoingcaesarean section using spinal anesthesia in Emergency Operating Theatre and Central Surgery Installation of Cipto Mangunkusumo Hospital were included in this study. Subarachnoid anaesthesia was performed in all patients. Those parturitions women were randomly divided into two groups. One group received bupivacaine 0.5%H 10 mg with adjuvant morphin HCL 0,1mg and chlonidine 15 mcg intrathecal and the other received bupivacaine 0.5%H 10 mg with adjuvant morphin HCL 0,1mg and NaCl 0.9% 0.1cc intrathecal. We observed incidence and degree of shivering at 5 minutes interval until 90 minutes. Tympanic temperature, hemodynamic parameter and adverse reactioon were recorded at 15 minutes interval until 90 minutes during the perioperative period.

Results: There was significant diff erence (p=0,000) incidence of shivering between two groups. In chlonidine groups 4 parturitions had shivering (4.49%), while in control groups 33parturitions (37,08%) had shivering. There was significant diff erence (p=0,000) between two groups in degree of shivering. In chlonidine groupsthe degree of shivering more lower than control groups. The decrease in core temperature in chlonidine groups more lower than control groups (p<0,005). There were no significant difference in nausea, vomitus and ephedrin used between two groups.

Conclusions: Addition of 15 mcg chlonidine intrathecal signifi cantly reduce the incidence and degree of shivering in the parturitions women undergoing caesarean section using spinal anesthesia.

Keywords: Spinal anesthesia, Shivering, chlonidine intrathecal


Full Text: Full Text in Bahasa Indonesia


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