LAXATIVE EFFECT OF LEAF TAMARIND JUICE (Tamarindus indica Linn.) ON WHITE RATS INDUCED WITH GAMBIER

Dian Sundari, M. Wien Winarno

Abstract


Plants tamarind (Tamarindus indica Linn.) known to the public as a shade tree and is found in almost all parts of Indonesia. The leaves are called "sinom" in the Java language is also used as a vegetable and medicine. Empirically java acid is used as a remedy gout, ulcers, boils, laxative, fever, menstrual facilitator, inflammation. Laxative effect has been studied (laxative) leaf juice tamarind (Tamarindus indica Linn.) Intestinal transit method and experimental animals used white rats. The dose tested was 3 doses of juice that is 20%, 40% and 60%, which is given orally. For purposes of comparison (positive control) is the granting of four Dulcolax ml/200 g bw., While distilled water as negative control. Two days before the experiment is done, all rats were induced constipation with gambier extract 3 g / kg bw. The experimental results showed that the average ratio of intestinal length traversed by charcoal proanalisa java acidic juice dose group 60%, 40%, 20%; Dulcolax and distilled water, respectively 49.86%, 60.2%, 18.34%, 75.22% and 2.01%. Showed statistically tamarind juice at doses of 40% has laxative properties, but smaller than the Dulcolax.

Keywords: laxative, white mice, Tamarindus indica Linn., leaves, tamarind juice


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